Publications

  1. Steele, N.G.*, Biffi, G.*, Kemp, S.B., Zhang, Y., Drouillard, D., Syu, L, Hao, Y, Oni, T.E., Brosnan, E. , Elyada, E., Doshi, A., Hansma, C., Espinoza, C., Abbas, A., The, S., Irizarry-Negron, V., Halbrook, C.J., Franks, N.E., Hoffman, M.T., Brown, K., Carpenter, E.S., Nwosu, Z., Johnson, C., Lima, F., Anderson, M.A., Park, Y., Crawford, H.C., Lyssiotis, C.A., Frankel, T.L., Rao, A., Bednar, F., Dlugosz, A.A., Preall, J.B., Tuveson, D.A., Allen, B.L., Pasca di Magliano, M.‡, Inhibition of Hedgehog signaling alters fibroblast composition in pancreatic cancer, Clin Cancer Res. 2021 Apr 1;27(7):2023-2037. doi: 10.1158/1078-0432.CCR-20-3715. Epub 2021 Jan 25. PMCID:  PMC8026631. (Cover Article
  1. Steele, N.G.*, Carpenter E,.S.*, Kemp S.B.*, Sirihorachai V.*, The, S., Delrosario, L., Lazarus, J., Amir, E.D., Gunchick, V., Espinoza, C., Bell, S., Harris, L., Lima, F., Irizarry-Negron, V., Paglia, D., Macchia, J., Chu, A.K.Y., Schofield, H., Wamsteker, E.J., Kwon, R., Schulman, A., Prabhu, A., Law, R., Sondhi, A., Yu, J., Patel, A., Donahue, K., Nathan, H., Cho, C., Anderson, M.A., Sahai, V., Lyssiotis, C.A., Zou, W., Allen B.L., Rao, A., Crawford, H.C., Bednar, F., Frankel, T.L., Pasca di Magliano, M.‡, Multimodal Mapping of the Tumor and Peripheral Blood Immune Landscape in Human Pancreatic Cancer, Nat Cancer. 2020, Nov; 1(11):  1097-1112. doi: 10.1038/s43018-020-00121-4. Epub 2020 Oct 26. PMCID: PMC8294470. 
  1. Echevarria-Andino, M.L., and Allen, B.L.‡, The Hedgehog Co-Receptor BOC Differentially Regulates SHH Signaling During Craniofacial Development, Development. 2020, Dec 14; 147(23):dev189076. doi: 10.1242/dev.189076. PMID:  33060130. PMCID:  PMC7758635.  
  1. Garcia, P.E., Adoumie, M., Kim, E.C., Zhang, Y., Scales, M.K., El-Tawil, Y.S., Shaikh, A.Z., Wen, H.J., Bednar, F., Allen, B.L., Wellik, D.M., Crawford, H.C., Pasca di Magliano, M., Differential Contribution of Pancreatic Fibroblasts Subsets to the Pancreatic Cancer Stroma, Cell Mol Gastroenterol Hepatol. 2020;10(3):581-599. doi: 10.1016/j.jcmgh.2020.05.004. Epub 2020 May 23. PMCID: PMC7399194
  1. Oh, Y.S., Wang, E.J., Gailey, C.D., Brautigan, D.L., Allen, B.L., and Fu, Z., Ciliopathy-Associated Protein Kinase ICK Requires Its Non-Catalytic Carboxyl-Terminal Domain for Regulation of Ciliogenesis, Cells.  2019 Jul 4;8(7). pii: E677. doi: 10.3390/cells8070677. PMCID:  PMC6678984. 
  1. Engelke, M.F., Waas, B., Kearns, S.E., Suber, A., Boss, A., Allen, B.L., and Verhey, K.J., Acute inhibition of heterotrimeric kinesin-2 function reveals mechanisms of intraflagellar transport in mammalian cilia, Curr Biol.  2019 Apr 1;29(7):1137-1148.e4. doi: 10.1016/j.cub.2019.02.043. Epub 2019 Mar 21. PMCID:  PMC6445692. 
  1. Razumilava, N., Shiota, J., Mohamad Zaki, N.H., Ocadiz-Ruiz, R., Cieslak, C.M., Zakharia, K., Allen, B.L., Gores, G.J., Samuelson, L.C., and Merchant, J.L., Hedgehog signaling modulates Interluekin-33-dependent extrahepatic bile duct epithelial cell proliferation in mice, Hepatol Commun., 2018, Dec 11; 3(2):  277-292. Doi:  10.1002/hep4. 1295. eCollection 2019 Feb. PMCID:  PMC6357834. 
  1. Orchard, P., White, J.S., Thomas, P.E., Mychalowych, A., Kiseleva, A., Hensley, J., Allen, B., Parker, S.C.J., and Keegan, C.E., Genome-wide chromatin accessibility and transcriptome profiling show minimal epigenome changes and coordinated transcriptional dysregulation of hedgehog signaling in Danforth’s short tail mice, Hum Mol Genet., 2018, Oct 31; doi: 10.1093/hmg/ddy378. [Epub ahead of print]. PMID:  30380057. 
  1. Kumari, A., Ermilov, A.E., Grachtchouk, M.A., Dlugosz, A.A., Allen, B.L., Bradley, R.M., and Mistretta, C.M., Recovery of taste organs and sensory function after severe loss from Hedgehog/Smoothened inhibition with cancer drug sonidegib, Proc Natl Acad Sci USA, 2017, Nov 28; 114(48):  E10369-E10378. PMCID:  PMC5715770. 
  1. Hong, M., Srivastava, K., Kim, S., Allen, B.L., Leahy, D.J., Hu, P., Roessler, E., Krauss, R.S., and Muenke, M., BOC is a Modifier Gene in Holoprosencephaly, Hum Mutat, 2017, Jul 4. doi:  10.1002/humu.23286. PMCID:  PMC5673120. 
  1. Pinskey, J.M., Franks, N.E., McMellen, A.N., Giger, R.J., and Allen, B.L.†, Neuropilin-1 promotes Hedgehog signaling through a novel cytoplasmic motif, J Biol Chem, 2017, Jun 30; pii: jbc.M117.783845. doi: 10.1074/jbc.M117.783845.  PMCID:  PMC5602381.